TAAM Director
Dr Yann HERAULT
The TAAM is a CNRS laboratory providing the scientific community with fundamental biomedical and pharmaceutical research. It offers the latter a collection of services related to the provision of murine models.
The mouse genome is 95% identical to that of the human being: this genetic proximity makes it a particularly well suited model for research on diseases affecting human.
The TAAM has 3 departments, each specialized in a specific field of competence:
• the CDTA (Département de Cryopréservation, Distribution, Typage et Archivage animal) is a centre for breeding and distributing transgenic and mutant mice in different states of healthsanitary status conditions. Its recognized technical expertise (axenization, in vitro fertilization, re-derivation,...), combined with the wealth of
strains available in its catalogue, makes it a leading player in the field of mouse model distribution.
• the CIPA (Centre d'Imagerie du Petit Animal) provides researchers with innovative 2D and 3D imaging equipment, allowing non-invasive exploration techniques to be developed.
Because of its close co-operation with high-tech industries, the CIPA is capable of implementing the most recent technologies.
• the SEAT (SErvice des Animaux Transgéniques) offers customized transgenic murine models (conventional and targeted transgenesis), and the production of modified ES cells. This laboratory also offers the possibility of developing transgenic strains from on-site generated founders.
We successfully expanding, end of 2011, the scope of certification ISO 9001 at the site of Villejuif for the activity of transgenesis. We also expanded the certification to Orleans site for Animal Technology activities and Research and Development activities. Now, almost all service activities are certified ISO 9001: 2008.
Since December 22, 2009, the Resource Center has not only expanded its certification service activity
to Health Control but has also managed its transition to the
2008 version of ISO 9001.
Staff involvement and commitment of management have enabled the achievement of objectives.
• Further information on the Quality Management ...
EMMA resource paper published in the NAR 2010 database issue.
• See the advanced access copy at
Nucleic Acids Research.
The recently launched EMMAservice project (January 2009 - December 2012) supports eligible customers
with free of charge 'Transnational Access' (TA) to a total of 330 access units from the available
EMMA mouse mutant resource.
• Read the whole documentation (PDF).
A partnership project with Key-Obs will further expand the range of available services by providing opportunities for academic or non-academic customers to use the services of the Resource Center for behavioral phenotyping.