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Cryopréservation, Distribution, Typage et Archivage animal (CDTA)

Breeding: services


Breeding and distribution of mice:

This service may be carried out in a breeding area/isolator or ventilated carrier cage, according to the desired health status and the customer's objective.

Examples : 
  - conservation and distribution of rare and/or fragile strains in small numbers, preservation of a high health status -> Breeding in isolators or ventilated carrier cages.
  - obtaining a large population (cross-breeding for conducting protocols) -> Breeding within specific areas.


On-site research work

Mouse axenization through caesarean procedures* :

This technique allows axenic animals to be obtained from mice with a conventional health status.

Gnotoxenization* :

This method allows for the provision of mice carrying known and controlled flora.

Sanitary Quarantine*

*Services only carried out within the isolator facility.


Health status definition


Axenic animals: animals obtained by means of an aseptic caesarian operation, free of any detectable micro-organisms.

Gnotoxenic animals: axenic animals which have been re-colonized by one or more known microorganisms.

SPF animals (Specific Pathogen Free): animals that are generally obtained by transferring embryos bred under barriers, in order to keep them free from any of the pathogens listed by FELASA (see FELASA recommandations)

SOPF animals: animals that are generally obtained by transferring embryos bred under a barrier, in order to keep them free from any opportunistic or pathogenic microorganisms listed by FELASA (see FELASA recommandations)

Conventional or holoxenic animals: animals that host a flora within which the absence of pathogenic or opportunistic agents cannot be guaranteed (see recommendation of the IBiSA work group).